What is Polyhexanide + Poloxamer and why should we look for these active ingredients in modern wound care?

When it comes to wound care , infection is the last thing we want. That's why modern medical products combine two active ingredients - polyhexanide and poloxamer . What is it and why are they so effective?

Polyhexanide – a gentle protector against infection

Polyhexanide (also known as PHMB or polyhexanide biguanide) is an antimicrobial agent that effectively kills bacteria, viruses, and fungi.

It has been used in healthcare for more than 20 years – and has several advantages:

  • Does not sting or irritate – gentle on sensitive skin and mucous membranes
  • It acts directly in the wound – destroying microorganisms where needed
  • Does not promote resistance – unlike antibiotics, bacteria do not "learn" to use it

These properties make it ideal for the care of acute and chronic wounds , burns or abrasions.

Poloxamer – gentle cleaner and helper

Poloxamer is a surfactant – simply put, it helps clean the wound without drying or damaging it.

It acts as an "emulsifier" - it removes impurities, old exudate (wound discharge) and allows effective penetration of polyhexanide into the tissues.

  • Facilitates wound cleaning without mechanical irritation
  • Ensures even coverage of the wound with antimicrobial agent
  • Promotes a more pleasant application of the product

Why are they so effective together?

The combination of polyhexanide and poloxamer brings the best of both worlds:

  • Polyhexanide kills bacteria – without pain
  • Poloxamer cleans and prepares the wound – without irritation

This combination is the basis of modern solutions, sprays and gels for moist wound healing. It is used in hospitals, home care and in products that are freely available to the public.

Summary: What to remember?

  • Polyhexanide + poloxamer = safe and effective wound care
  • Suitable for sensitive, irritated or damaged skin
  • No burning, no antibiotics, with protection against infection
  • Ideal for children, seniors, chronic wounds and minor injuries

👉 Final tip: Look for these substances on the product packaging or ask your doctor or pharmacist - especially if you are looking for a gentle solution without alcohol and antibiotics.

You can also find products with this combination with us, for example, antimicrobial spray or Actolind gel.

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